The El Escorial criteria: strengths and weaknesses.
نویسندگان
چکیده
The El Escorial criteria for the diagnosis of amyotrophic lateral sclerosis (ALS) were established 20 years ago and have been used as inclusion criteria for clinical trials. However, concerns have been raised concerning their use as diagnostic criteria in clinical practice. Moreover, as modern genetics have shed new light on the heterogeneity of ALS and the close relationship between ALS and frontotemporal dementia (FTD) recognized, the World Federation of Neurology Research Group on ALS/MND has initiated discussions to amend and update the criteria, while preserving the essential components for clinical trial enrolment purposes.
منابع مشابه
Awaji criteria for the diagnosis of amyotrophic lateral sclerosis:a systematic review.
OBJECTIVE To estimate the potential diagnostic added value of the Awaji criteria for diagnosis of a myotrophiclateral sclerosis (ALS), which have been compared with the previously accepted gold standard the revised El Escorial criteria in several studies. DATA SOURCES MEDLINE and Web of Science (until October2011). STUDY SELECTION We searched for studies testing the diagnostic accuracy of t...
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ورودعنوان ژورنال:
- Amyotrophic lateral sclerosis & frontotemporal degeneration
دوره 16 1-2 شماره
صفحات -
تاریخ انتشار 2015